By Daniela López-MaldonadoFor years, researchers have tried to understand the biological basis of what makes people produce insulin, but little has been done to understand how it is produced.
Now, a team of scientists led by Miguel D. Bocanegra at the Institute of Biomedical and Bioengineering of the University of Bocan in Portugal has developed a novel method that uses an approach called “targeted bioprinting” that mimics the process of the pancreas.
By using a targeted bioprosthesis approach, the researchers could develop an insulin that can be injected directly into the pancrea and which can mimic the insulin produced by the human pancrease.
The researchers say they have developed a unique insulin which can deliver an accurate dose of insulin directly to the pancreatic ducts and not require insulin injections.
The team says that the insulin works in a similar way to insulin used in the human body, but has a smaller range of targets.
The method could help doctors develop new medications for diabetes, cancer and heart disease, the authors wrote.
Bocanega is a member of the International Center for Bioengineering and Bioenergistics at the University Hospital of São Paulo, and was also the lead author of a previous paper describing the method.
The work was published online this week in Science Advances.
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